Home

About Us

Student Login

Tuition Fees

Donations

Sponsors

Radio Show

Conferences

Links

Contact Us

Go To Applied BioPhysics Foundation

Request Information

Go To "Ask Mom" Radio Show

Presentation to the CDC March 2002 Part 3

 
Figure 6. Normal MRC-5 fibroblasts seen under phase contrast microscopy.

Figure 6

Note the rather bland appearing, closely inter-digitating spindle shaped cells. Many cell types can be used to demonstrate the cytopathic effects of stealth viruses.

Figure 7. MRC-5 fibroblasts following exposure to mononuclear cells from a stealth virus infected patients.

Figure 7

The cells become enlarged and rounded, with a tendency to form large clusters. The cytoplasm develops a foamy vacuolated appearance. Intracellular pigmented material will commonly develop, especially in long term cultures.

Figure 8. Cell clusters in a long-term stealth virus culture

Figure 8

showing the accumulation of dark pigmented material and formation of long ribbon shaped structures. Relatively normal appearing cells, that grew outfrom the top left cluster, can be seen.

Figure 9. Electron microscopic appearance of a stealth virus infected MRC-5 cell.

Figure 9

The culture was from a patient involved in a1996 outbreak of stealth virus infection in the Mohave Valley region of the US. The marked vacuolization is similar to that shown in Figure 4.

Figure 10. Electron microscopy of a stealth virus infected cell showing widespread accumulations of particulate materials and lipid-filledvacuoles.

Figure 10

Unlike infections with many conventional viruses, it is rather uncommon to see intact viral particles.
 



 


 



 


 



 



 


 


 


 

EMAIL

Copyright 2006 Progressive University